Accelerated NGS analysis in AI cloud (GPU cloud) ================================================ Objective --------- Current Next Generation Sequence (NGS) analysis pipelines are run on CPU-platforms and take a long time to complete (e.g., days). In this session, we will discuss how to reduce the processing time of NGS analysis pipelines using GPU-platforms. Content ------- - `Introduction to concepts used in the lecture `__ - Next Generation Sequencing (NGS) - Main steps of DNA sequencing - Exome sequencing workflow - `NGS data analysis and precision genomics applications `__ - Sequence data analysis - Precision genomics - definition - Main steps in sequence analysis workflows - Precision genomics in routine clinical practice - `Why accelerate genomics workflows? `__ - GPUs vs NGS - `CPU-only and GPU-only workflows `__ - NVIDIA Clara Parabricks - NAIC (Norwegian AI Cloud) workflows: CPU-only and GPU-only - `Evaluation of CPU-only vs GPU-only workflows `__ - Testing workflows using sample data sets - Processing time of CPU-only vs GPU-only workflows - Performance on different NVIDIA GPU products - `Biological relevance of GPU-only compared to CPU-only `__ - `Concerns and summary `__ - `Hands-on experiment `__ Author/Instructor ----------------- - Pubudu Saneth Samarakoon